Advances in Platelet Function Testing—Light Transmission Aggregometry and Beyond
نویسندگان
چکیده
منابع مشابه
Development of North American consensus guidelines for medical laboratories that perform and interpret platelet function testing using light transmission aggregometry.
Platelet function testing is important for the diagnostic evaluation of common and rare bleeding disorders. Our study goals were to promote best practices and reduce unnecessary testing variances by developing North American guidelines on platelet function testing. Guidelines were developed by consensus for expert recommendations (minimum level for approval, 70%) that included recommendations o...
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Traditionally, platelets have been thought of as anuclear, subcellular fragments derived from megakaryocytes circulating in blood as small discs and mitigating hemorrhage. This hemostatic process requires platelet activation, a complex chain of events involving rapid structural changes that activate adhesion receptors, remodel the cytoskeleton, and lead to the eventual synthesis and secretion o...
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Platelet aggregation inhibition is mandatory for patients undergoing percutaneous coronary intervention (PCI) [1]. High on-treatment plate-let reactivity is an important independent risk factor for the occurrence of thrombotic and ischemic events after PCI [2]. Some point of care platelet aggregation assays are currently used in daily practice as a substitute for more expensive and time consumi...
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ژورنال
عنوان ژورنال: Journal of Clinical Medicine
سال: 2020
ISSN: 2077-0383
DOI: 10.3390/jcm9082636